SCHEMBL14499207

SCHEMBL14499207

C[n+]1ccn(CCCCCCn2cc[n+](C)c2)c1

nearest known ligand 0.81

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.81
MEN1 O00255 2/20 0.81
HSP90AA1 P07900 2/20 0.81
KMT2A Q03164 2/20 0.81
APAF1 O14727 1/20 0.81
NPC1 O15118 1/20 0.81
PLA2G1B P04054 1/20 0.81
MAPT P10636 1/20 0.81
MAPK1 P28482 1/20 0.81
HTT P42858 1/20 0.81
RAB9A P51151 1/20 0.81
NPSR1 Q6W5P4 1/20 0.81
ATG4B Q9Y4P1 1/20 0.81
FDPS P14324 13/20 0.40
LMNA P02545 1/20 0.38
PON1 P27169 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12220260 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL12220249 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL17395302 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL12220251 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL12220228 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL12220261 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
SCHEMBL17395283 1.00 SMN1; SMN2 (0.81) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Iodide SCHEMBL2531281 0.98 SMN1; SMN2 (0.78) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Iodide SCHEMBL2533638 0.98 SMN1; SMN2 (0.78) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1
Iodide SCHEMBL2532625 0.98 SMN1; SMN2 (0.78) SMN1; SMN2MEN1HSP90AA1KMT2AAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987450-B2 Luminescent gold(III) compounds for organic light-emitting devices and their preparation THE UNIVERSITY OF HONG KONG (CN) 2015-03-24 US disclosed
US-20130193428-A1 LUMINESCENT GOLD(III) COMPOUNDS FOR ORGANIC LIGHT-EMITTING DEVICES AND THEIR PREPARATION THE UNIVERSITY OF HONG KONG (CN) 2013-08-01 US disclosed
US-20130164748-A1 Detection of nucleic acid amplification APPLIED BIOSYSTEMS LLC (US) 2013-06-27 US disclosed
US-20070099211-A1 Detection of nucleic acid amplification APPLIED BIOSYSTEMS, LLC 2007-05-03 US disclosed