Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680937 | 0.93 | PDK2 (0.41) | MAOAMAOBPDK2BCL2MCL1 | |
| SCHEMBL29512070 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL22000499 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL1338609 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL16200615 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL1753495 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL3793714 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL17014867 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL14340229 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 | |
| SCHEMBL30838743 | 0.89 | PDK2 (0.46) | PDK2SLC6A4MLNRNR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229702-B2 | Oligofluorenlylene compounds | CANON KABUSHIKI KAISHA (JP) | 2007-06-12 | — | — | US | disclosed |