Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.73 |
| ▸ | HBB | P68871 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | EDNRA | P25101 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.66 |
| ▸ | POLG | P54098 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501172 | 0.98 | PNP (0.73) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL14501071 | 0.95 | MEN1 (0.68) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL14501100 | 0.94 | MEN1 (0.67) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL14501171 | 0.94 | PNP (0.67) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL12088904 | 0.90 | PNP (0.71) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL8445568 | 0.90 | MEN1 (0.73) | PNPHBBBLMTSHRUSP2 | |
| Glycyl Ester Of Acyclovir SCHEMBL10502091 | 0.90 | PNP (0.71) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL14501173 | 0.90 | MEN1 (0.65) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL14421640 | 0.88 | PNP (0.74) | PNPHBBBLMTSHRUSP2 | |
| SCHEMBL8842958 | 0.88 | PNP (0.69) | PNPHBBBLMTSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214710-B2 | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214710-B2 | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |