Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501365 | 0.89 | PPARG (0.46) | PPARGPPARDPPARAFFAR1PTGS2 | |
| SCHEMBL4685048 | 0.87 | PPARG (0.60) | PPARGPPARDPPARAFFAR1PTGS2 | |
| SCHEMBL4685042 | 0.87 | PPARG (0.60) | PPARGPPARDPPARAFFAR1PTGS2 | |
| SCHEMBL28981586 | 0.83 | CYP1A1 (0.64) | PTGS2CYP1A1CYP1B1HDAC6MAPK1 | |
| SCHEMBL28981584 | 0.83 | CYP1A1 (0.64) | PTGS2CYP1A1CYP1B1HDAC6MAPK1 | |
| SCHEMBL3927973 | 0.83 | GAA (0.53) | PTGS2MAPK1KDM4EGAA | |
| SCHEMBL14501312 | 0.82 | CYSLTR2 (0.59) | PPARGPPARAPTGS2CYP1A2CYSLTR2 | |
| SCHEMBL4683424 | 0.77 | PPARG (0.58) | PPARGPPARDPPARAFFAR1PTGS2 | |
| SCHEMBL4683420 | 0.77 | PPARG (0.58) | PPARGPPARDPPARAFFAR1PTGS2 | |
| SCHEMBL21224752 | 0.75 | GAA (0.46) | PTGS2MAPK1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |