Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.65 |
| ▸ | PPARG | P37231 | 18/20 | 0.65 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364287 | 1.00 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL5363024 | 0.93 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL14501941 | 0.93 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL14501939 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5364766 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5358907 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5364761 | 0.88 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL14501938 | 0.88 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5361860 | 0.88 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5352920 | 0.83 | PPARA (0.60) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |