Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124033 | 0.90 | PTGDR2 (0.68) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4124034 | 0.90 | PTGDR2 (0.68) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4128853 | 0.84 | PTGDR2 (0.59) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6278727 | 0.84 | PTGDR2 (0.59) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4128847 | 0.84 | PTGDR2 (0.59) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4132877 | 0.84 | PTGDR2 (0.58) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4132875 | 0.84 | PTGDR2 (0.58) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4123926 | 0.82 | PTGDR2 (0.82) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4138016 | 0.81 | PTGDR2 (0.60) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4138012 | 0.81 | PTGDR2 (0.60) | PTGDR2LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211672-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-7211672-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-01 | — | — | US | disclosed |