Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497241 | 0.91 | PTGDR2 (0.50) | PTGDR2MEN1KMT2A | |
| SCHEMBL4122274 | 0.91 | PTGDR2 (0.50) | PTGDR2MEN1KMT2A | |
| SCHEMBL4121805 | 0.91 | PTGDR2 (0.50) | PTGDR2MEN1KMT2A | |
| SCHEMBL13776069 | 0.90 | PTGDR2 (0.63) | PTGDR2MEN1KMT2A | |
| SCHEMBL4124172 | 0.86 | PTGDR2 (0.53) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4124175 | 0.86 | PTGDR2 (0.53) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4128526 | 0.85 | PTGDR2 (0.57) | PTGDR2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4128528 | 0.85 | PTGDR2 (0.57) | PTGDR2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4114085 | 0.84 | PTGDR2 (0.80) | PTGDR2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4114090 | 0.84 | PTGDR2 (0.80) | PTGDR2MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211672-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-7211672-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-05-01 | — | — | US | disclosed |