Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.38 |
| ▸ | PPARA | Q07869 | 13/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418984 | 0.94 | PPARG (0.38) | PPARGPPARAHDAC6PPARDSIGMAR1 | |
| SCHEMBL14503189 | 0.93 | PPARG (0.45) | PPARGPPARAPDE10APPARD | |
| SCHEMBL5420546 | 0.89 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL5408384 | 0.88 | PPARG (0.36) | PPARGPPARAPPARD | |
| SCHEMBL5766872 | 0.87 | PPARG (0.45) | PPARGPPARAHDAC6PPARD | |
| SCHEMBL5408608 | 0.87 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL5768768 | 0.86 | PPARG (0.44) | PPARGPPARAHDAC6PPARD | |
| SCHEMBL5768781 | 0.86 | PPARG (0.44) | PPARGPPARAHDAC6PPARD | |
| SCHEMBL5768772 | 0.86 | PPARG (0.38) | PPARGPPARAHDAC6PPARD | |
| SCHEMBL5408965 | 0.86 | PPARG (0.49) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220864-B2 | Dihydronaphthalene derivative compounds and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220864-B2 | Dihydronaphthalene derivative compounds and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |