Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376496 | 0.85 | MAPT (0.47) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6493482 | 0.72 | MAPT (0.60) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6490197 | 0.72 | MAPT (0.60) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14503208 | 0.71 | MAPT (0.69) | MAPTLMNANPSR1HTTMAPK1 | |
| SCHEMBL6493235 | 0.71 | KMT2A (0.61) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8923080 | 0.70 | KMT2A (0.64) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14503638 | 0.70 | MAPT (0.53) | MAPTALDH1A1LMNANPSR1HTT | |
| SCHEMBL14503190 | 0.68 | HTT (0.64) | MAPTALDH1A1NPSR1HTTUSP2 | |
| SCHEMBL6239397 | 0.68 | GBA1 (0.62) | MAPTKDM4ELMNAHPGDNPSR1 | |
| SCHEMBL6238044 | 0.68 | GBA1 (0.62) | MAPTKDM4ELMNAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |