Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.33 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.33 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.33 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ATIC | P31939 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13088704 | 0.81 | TP53 (0.44) | PTPN11BRD4TP53CREBBPSENP2 | |
| SCHEMBL14451206 | 0.81 | PTPN11 (0.41) | PTPN11TP53SENP2SUMO2SUMO1 | |
| SCHEMBL14503632 | 0.80 | PTPN11 (0.40) | PTPN11SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL12052556 | 0.80 | PTPN11 (0.40) | PTPN11BRD4ALDH1A1MAPT | |
| SCHEMBL6123828 | 0.79 | PTPN11 (0.37) | PTPN11BRD4TP53CREBBPSENP2 | |
| SCHEMBL13860897 | 0.78 | PTPN11 (0.40) | PTPN11BRD4TP53CREBBPSENP2 | |
| SCHEMBL14451199 | 0.78 | PTPN11 (0.40) | PTPN11TP53SENP2SUMO2SUMO1 | |
| SCHEMBL13298506 | 0.77 | PTPN11 (0.38) | PTPN11SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL13419025 | 0.77 | PTPN11 (0.40) | PTPN11BRD4RECQL | |
| SCHEMBL13802980 | 0.76 | PTPN11 (0.47) | PTPN11SENP2SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217803-B2 | Benzimidazole-pyridone-based azo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-15 | — | — | US | disclosed |