Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249365 | 0.92 | EPHX2 (0.78) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4246762 | 0.90 | EPHX2 (0.86) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4250879 | 0.89 | EPHX2 (0.84) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4253940 | 0.89 | EPHX2 (0.91) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4245860 | 0.88 | EPHX2 (0.86) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4250475 | 0.88 | EPHX2 (0.83) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4252922 | 0.87 | EPHX2 (0.82) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4252988 | 0.87 | EPHX2 (0.82) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4249386 | 0.87 | EPHX2 (0.82) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4252931 | 0.87 | EPHX2 (0.82) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067836-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |