Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NDUFS8 | O00217 | 5/20 | 0.41 |
| ▸ | COXFA4 | O00483 | 5/20 | 0.41 |
| ▸ | NDUFAB1 | O14561 | 5/20 | 0.41 |
| ▸ | NDUFA1 | O15239 | 5/20 | 0.41 |
| ▸ | NDUFS4 | O43181 | 5/20 | 0.41 |
| ▸ | NDUFB5 | O43674 | 5/20 | 0.41 |
| ▸ | NDUFB3 | O43676 | 5/20 | 0.41 |
| ▸ | NDUFC1 | O43677 | 5/20 | 0.41 |
| ▸ | NDUFA2 | O43678 | 5/20 | 0.41 |
| ▸ | NDUFS5 | O43920 | 5/20 | 0.41 |
| ▸ | NDUFS7 | O75251 | 5/20 | 0.41 |
| ▸ | NDUFS2 | O75306 | 5/20 | 0.41 |
| ▸ | NDUFS6 | O75380 | 5/20 | 0.41 |
| ▸ | NDUFB1 | O75438 | 5/20 | 0.41 |
| ▸ | NDUFS3 | O75489 | 5/20 | 0.41 |
| ▸ | NDUFB6 | O95139 | 5/20 | 0.41 |
| ▸ | NDUFA3 | O95167 | 5/20 | 0.41 |
| ▸ | NDUFB4 | O95168 | 5/20 | 0.41 |
| ▸ | NDUFB8 | O95169 | 5/20 | 0.41 |
| ▸ | NDUFB2 | O95178 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495421 | 0.91 | CYP3A4 (0.42) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13714667 | 0.88 | CYP3A4 (0.49) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13714733 | 0.88 | CYP3A4 (0.49) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13714665 | 0.88 | CYP3A4 (0.49) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13743063 | 0.88 | CYP3A4 (0.47) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13962606 | 0.86 | CYP3A4 (0.47) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL13714668 | 0.80 | CYP3A4 (0.59) | CA12CA1CA7CA9CA13 | |
| SCHEMBL13714673 | 0.80 | CYP3A4 (0.59) | CA12CA1CA7CA9CA13 | |
| SCHEMBL13714872 | 0.80 | CYP3A4 (0.59) | CA12CA1CA7CA9CA13 | |
| SCHEMBL13714894 | 0.80 | CYP3A4 (0.68) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230027-B2 | Anti-first-pass effect compounds | BIOAVAILABILITY SYSTEMS, L.L.C. (US) | 2007-06-12 | — | — | US | disclosed |