Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 16/20 | 0.46 |
| ▸ | GAA | P10253 | 16/20 | 0.46 |
| ▸ | SI | P14410 | 16/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 16/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14512365 | 0.92 | MGAM (0.56) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL14512480 | 0.91 | MGAM (0.39) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512144 | 0.90 | MAPT (0.41) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512200 | 0.90 | FFAR4 (0.42) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512404 | 0.88 | MAPT (0.39) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512484 | 0.88 | MGAM (0.49) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512226 | 0.86 | MGAM (0.47) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL14512489 | 0.85 | MGAM (0.47) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL14512227 | 0.85 | MGAM (0.58) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL14512356 | 0.84 | MGAM (0.56) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |