SCHEMBL1451345

SCHEMBL1451345

COC(c1cc([B-](c2cc(C(F)(F)F)cc(C(OC)(C(F)(F)F)C(F)(F)F)c2)(c2cc(C(F)(F)F)cc(C(OC)(C(F)(F)F)C(F)(F)F)c2)c2cc(C(F)(F)F)cc(C(OC)(C(F)(F)F)C(F)(F)F)c2)cc(C(F)(F)F)c1)(C(F)(F)F)C(F)(F)F.[Tl+]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
IDO1 P14902 2/20 0.32
RORC P51449 2/20 0.31
CES2 O00748 1/20 0.31
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29830717 1.00 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
SCHEMBL984942 0.98 NR1H2 (0.34) NR1H2NR1H3IDO1RORCCES2
SCHEMBL18315374 0.98 NR1H2 (0.34) NR1H2NR1H3IDO1RORCCES2
SCHEMBL29831166 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
Silver SCHEMBL29830991 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
SCHEMBL1451396 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
Lithium Ion SCHEMBL29830873 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
Lithium Ion SCHEMBL1452309 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
Silver SCHEMBL1452073 0.96 NR1H2 (0.33) NR1H2NR1H3IDO1RORCCES2
SCHEMBL1451577 0.94 NR1H2 (0.36) NR1H2NR1H3RORCNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1034196-B1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS PROMERUS LLC (US) 2005-01-12 EP claimed
US-6455650-B1 CONTACTING POLYCYCLOOLEFIN MONOMER WITH A HIGH ACTIVITY GROUP 10 TRANSITION METAL CATALYST COMPLEX TO OBTAIN POLYMER PRODUCT THE B.F. GOODRICH COMPANY 2002-09-24 US claimed
US-20020052454-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS SUMITOMO BAKELITE CO., LTD. (JP) 2002-05-02 US claimed
US-20240279251-A1 Monomer, Polymerizable Composition, and Polymers Derived Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2024-08-22 US disclosed
WO-2024095078-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-05-10 WO disclosed
US-20240002586-A1 CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2024-01-04 US disclosed
US-7910674-B2 Especially a copolymer of norbornene and/or alkylnorbornene and (trialkoxysilylalkyl)norbornene; optical articles such as ophthalmic lenses, wave guides, optical fibers, and optical adhesives PROMERUS, LLC (US) 2011-03-22 US disclosed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US disclosed
EP-1155057-B1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES SUMITOMO BAKELITE CO (JP) 2005-06-22 EP disclosed
US-6903171-B2 Polymerized cycloolefins using transition metal catalyst and end products thereof PROMERUS, LLC (US) 2005-06-07 US disclosed
EP-1034196-B1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS PROMERUS LLC (US) 2005-01-12 EP disclosed
US-20030181607-A1 Polymerized cycloolefins using transition metal catalyst and end products thereof SUMITOMO BAKELITE CO., LTD. (JP) 2003-09-25 US disclosed
US-20030120006-A1 In mold addition polymerization of norbornene-type monomers using group 10 metal complexes THE B.F. GOODRICH COMPANY 2003-06-26 US disclosed
US-6538087-B2 (hetero)polycyclic polymer PROMERUS, LLC 2003-03-25 US disclosed
US-20030023013-A1 Catalyst and methods for polymerizing cycloolefins THE B.F.GOODRICH COMPANY 2003-01-30 US disclosed
US-6455650-B1 CONTACTING POLYCYCLOOLEFIN MONOMER WITH A HIGH ACTIVITY GROUP 10 TRANSITION METAL CATALYST COMPLEX TO OBTAIN POLYMER PRODUCT THE B.F. GOODRICH COMPANY 2002-09-24 US disclosed
US-20020103317-A1 Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same SUMITOMO BAKELITE CO., LTD. (JP) 2002-08-01 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
US-20020052454-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS SUMITOMO BAKELITE CO., LTD. (JP) 2002-05-02 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279251-A1 Monomer, Polymerizable Composition, and Polymers Derived Therefrom PBRM1, CARM1, WASF2 NR1H2 3334/4885NR1H3 3383/4885IDO1 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.