Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 11/20 | 1.00 |
| ▸ | SUV39H1 | O43463 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | FNTA | P49354 | 1/20 | 1.00 |
| ▸ | FNTB | P49356 | 1/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 1/20 | 1.00 |
| ▸ | RNF31 | Q96EP0 | 1/20 | 1.00 |
| ▸ | RBCK1 | Q9BYM8 | 1/20 | 1.00 |
| ▸ | SHARPIN | Q9H0F6 | 1/20 | 1.00 |
| ▸ | EP300 | Q09472 | 6/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gliotoxin SCHEMBL4294337 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL9667270 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL12149513 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL13341245 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL12018743 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL12618354 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL14579856 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL14986985 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL54420 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL20199940 | 1.00 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223554-B2 | Inhibitors of proteasomal activity for stimulating hair growth | OSTEOSCREEN, LTD. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223554-B2 | Inhibitors of proteasomal activity for stimulating hair growth | OSTEOSCREEN, LTD. (US) | 2007-05-29 | — | — | US | disclosed |