Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12991159 | 0.87 | PDE5A (0.68) | PDE5A | |
| SCHEMBL4977132 | 0.84 | PDE5A (0.61) | PDE5A | |
| SCHEMBL5248876 | 0.84 | PDE5A (0.61) | PDE5A | |
| SCHEMBL4977144 | 0.84 | PDE5A (0.61) | PDE5A | |
| SCHEMBL5248886 | 0.84 | PDE5A (0.61) | PDE5A | |
| SCHEMBL14514212 | 0.83 | PDE5A (0.62) | PDE5A | |
| SCHEMBL1679812 | 0.81 | PDE5A (0.75) | PDE5A | |
| SCHEMBL1679815 | 0.81 | PDE5A (0.75) | PDE5A | |
| SCHEMBL8488147 | 0.80 | PDE5A (0.57) | PDE5A | |
| SCHEMBL1680203 | 0.77 | PDE5A (0.60) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220736-B2 | Pyrimidine compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220736-B2 | Pyrimidine compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |