Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231386 | 0.95 | CYP3A4 (0.82) | CYP3A4CYP2D6 | |
| SCHEMBL14469250 | 0.91 | CYP3A4 (0.76) | CYP3A4CYP2D6 | |
| SCHEMBL14469271 | 0.90 | CYP3A4 (0.75) | CYP3A4CYP2D6 | |
| SCHEMBL8229191 | 0.89 | CYP3A4 (1.00) | CYP3A4CYP2D6 | |
| SCHEMBL14515307 | 0.87 | CYP3A4 (0.82) | CYP3A4CYP2D6 | |
| SCHEMBL12205315 | 0.86 | CYP3A4 (0.69) | CYP3A4CYP2D6 | |
| SCHEMBL14515299 | 0.86 | CYP3A4 (0.79) | CYP3A4CYP2D6 | |
| SCHEMBL14515301 | 0.86 | CYP3A4 (1.00) | CYP3A4CYP2D6 | |
| SCHEMBL14469602 | 0.84 | CYP3A4 (0.85) | CYP3A4CYP2D6 | |
| SCHEMBL8229202 | 0.84 | CYP3A4 (1.00) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220735-B2 | Benzimidazolone histamine H3 antagonists | SCHERING CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220735-B2 | Benzimidazolone histamine H3 antagonists | SCHERING CORPORATION (US) | 2007-05-22 | — | — | US | disclosed |