Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726782 | 0.94 | TLR7 (0.67) | TLR7TLR8 | |
| SCHEMBL3970742 | 0.92 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL13721619 | 0.90 | TLR7 (0.59) | TLR7TLR8 | |
| SCHEMBL13722251 | 0.90 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL3973006 | 0.89 | TLR7 (0.67) | TLR7TLR8 | |
| SCHEMBL14516464 | 0.89 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL3814801 | 0.88 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL3821653 | 0.88 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL3970553 | 0.88 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL3972922 | 0.88 | TLR7 (0.68) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199131-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7199131-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-04-03 | — | — | US | disclosed |