SCHEMBL14516522

SCHEMBL14516522

COCCc1nc2c(N)nc3ccccc3c2n1CCCCNS(=O)(=O)c1cccc(OC)c1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13721872 0.94 TLR7 (0.59) TLR7
SCHEMBL13721862 0.92 TLR7 (0.63) TLR7
SCHEMBL728626 0.92 TLR7 (0.64) TLR7
SCHEMBL13721577 0.91 TLR7 (0.58) TLR7
SCHEMBL13721852 0.91 TLR7 (0.58) TLR7
SCHEMBL14516523 0.91 TLR7 (0.59) TLR7
SCHEMBL3969990 0.91 TLR7 (0.63) TLR7
SCHEMBL14516569 0.91 TLR7 (0.57) TLR7
SCHEMBL726742 0.91 TLR7 (0.57) TLR7
SCHEMBL13721794 0.91 TLR7 (0.59) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7199131-B2 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-04-03 — — US disclosed
US-7199131-B2 Sulfonamide and sulfamide substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-04-03 — — US disclosed
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