Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 19/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 19/20 | 0.65 |
| ▸ | KCNQ5 | Q9NR82 | 6/20 | 0.65 |
| ▸ | KCNE1 | P15382 | 10/20 | 0.65 |
| ▸ | KCNQ1 | P51787 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180974 | 0.89 | KCNQ3 (0.76) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL5343768 | 0.80 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL5345718 | 0.79 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL5348385 | 0.79 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL14516635 | 0.78 | KCNQ3 (0.79) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL14516666 | 0.76 | KCNQ3 (0.77) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL14516674 | 0.76 | KCNQ3 (0.81) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL14516668 | 0.76 | KCNQ3 (0.71) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL14516690 | 0.75 | KCNQ3 (0.75) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL6184087 | 0.75 | KCNQ3 (1.00) | KCNQ3KCNQ2KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205307-B2 | Pyrimidines as novel openers of potassium ion channels | ICAGEN, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205307-B2 | Pyrimidines as novel openers of potassium ion channels | ICAGEN, INC. (US) | 2007-04-17 | — | — | US | disclosed |