Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14517997 | 0.95 | MAPT (0.41) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL12920787 | 0.83 | MAPT (0.46) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL9225609 | 0.83 | MAPT (0.54) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL557468 | 0.82 | MAPT (0.45) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL14564436 | 0.82 | MAPT (0.45) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL13210783 | 0.82 | NTRK1 (0.51) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL14564442 | 0.82 | MAPT (0.44) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL14564507 | 0.82 | CHRM3 (0.47) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL14564410 | 0.82 | MAPT (0.44) | MAPTHTTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL12212660 | 0.81 | MAPT (0.54) | MAPTHTTKDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208169-B2 | Biphenyl carboxamides | BAYER CROPSCIENCE LP (DE) | 2007-04-24 | — | — | US | disclosed |
| US-7208169-B2 | Biphenyl carboxamides | BAYER CROPSCIENCE LP (DE) | 2007-04-24 | — | — | US | disclosed |