Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518344 | 0.93 | CALCRL (1.00) | CALCRL | |
| SCHEMBL14518337 | 0.91 | CALCRL (1.00) | CALCRL | |
| SCHEMBL14518345 | 0.90 | CALCRL (1.00) | CALCRL | |
| SCHEMBL14518336 | 0.90 | CALCRL (1.00) | CALCRL | |
| SCHEMBL12362509 | 0.85 | CALCRL (0.74) | CALCRL | |
| SCHEMBL12431326 | 0.81 | CALCRL (1.00) | CALCRL | |
| SCHEMBL12430760 | 0.81 | CALCRL (1.00) | CALCRL | |
| SCHEMBL14518369 | 0.81 | CALCRL (1.00) | CALCRL | |
| SCHEMBL12362507 | 0.77 | CALCRL (0.74) | CALCRL | |
| SCHEMBL12431321 | 0.76 | CALCRL (0.76) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |