Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518330 | 0.90 | CALCRL (1.00) | CALCRL | |
| SCHEMBL14518354 | 0.90 | CALCRL (0.87) | CALCRL | |
| SCHEMBL14518334 | 0.82 | CALCRL (1.00) | CALCRL | |
| SCHEMBL4630136 | 0.79 | CALCRL (0.79) | CALCRL | |
| SCHEMBL14518349 | 0.79 | CALCRL (0.78) | CALCRL | |
| SCHEMBL4629911 | 0.79 | CALCRL (0.78) | CALCRL | |
| SCHEMBL4629280 | 0.78 | CALCRL (0.83) | CALCRL | |
| SCHEMBL14518339 | 0.78 | CALCRL (0.77) | CALCRL | |
| SCHEMBL4307354 | 0.78 | CALCRL (0.83) | CALCRL | |
| SCHEMBL14518351 | 0.78 | CALCRL (0.88) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202251-B2 | Bicyclic anilide spirohydantoin CGRP receptor antagonists | MERCK & CO., INC. (US) | 2007-04-10 | — | — | US | disclosed |