SCHEMBL14519084

SCHEMBL14519084

O=NC(=O)C1=NN(c2ccccc2)C(=O)C1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.71
GAA P10253 8/20 0.58
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 3/20 0.53
CYP1A2 P05177 1/20 0.53
CHRM2 P08172 1/20 0.53
CYP3A4 P08684 1/20 0.53
CHRM1 P11229 1/20 0.53
TSHR P16473 1/20 0.53
PTGS1 P23219 1/20 0.53
DRD3 P35462 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
SHMT2 P34897 1/20 0.49
LOX P28300 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3408946 0.83 POLB (1.00) POLBGAAMAPTMEN1KMT2A
SCHEMBL2857386 0.81 POLB (0.76) POLBGAAMAPTMEN1KMT2A
SCHEMBL12194201 0.77 POLB (0.69) POLBGAAMAPTMEN1KMT2A
SCHEMBL4908008 0.77 GAA (0.72) POLBGAAMAPTMEN1KMT2A
SCHEMBL14608274 0.74 POLB (0.76) POLBGAAMAPTMEN1KMT2A
SCHEMBL3407816 0.74 GAA (1.00) POLBGAAMAPTMEN1KMT2A
SCHEMBL7407077 0.73 POLB (0.64) POLBGAAMAPTMEN1KMT2A
Methyl Alcohol SCHEMBL11812087 0.73 GAA (0.97) POLBGAAMAPTMEN1KMT2A
SCHEMBL25078331 0.72 POLB (0.73) POLBGAAMAPTMEN1KMT2A
SCHEMBL13597571 0.71 POLB (0.76) POLBGAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1798804-A1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICES Nippon Kayaku Kabushiki Kaisha (JP) 2007-06-20 EP disclosed