Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254171 | 1.00 | KCNH2 (0.65) | KCNH2SLC2A1ALDH1A1LMNAPOLB | |
| SCHEMBL5257022 | 0.88 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5255571 | 0.88 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5258498 | 0.87 | KCNH2 (0.64) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL5255393 | 0.87 | KCNH2 (0.64) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL5258502 | 0.87 | KCNH2 (0.64) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL5251668 | 0.82 | KCNH2 (0.74) | KCNH2SLC2A1 | |
| SCHEMBL5254892 | 0.82 | KCNH2 (0.74) | KCNH2SLC2A1 | |
| SCHEMBL5309364 | 0.81 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL5252947 | 0.81 | SLC2A1 (0.64) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205408-B2 | Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents | SMITHKLINE BEECHAM, P.L.C. (GB) | 2007-04-17 | — | — | US | disclosed |
| US-7205408-B2 | Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents | SMITHKLINE BEECHAM, P.L.C. (GB) | 2007-04-17 | — | — | US | disclosed |