Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677340 | 0.85 | DPP4 (0.38) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL13676979 | 0.81 | DPP4 (0.38) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5233718 | 0.74 | DPP4 (0.35) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5228676 | 0.68 | DPP4 (0.41) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5227629 | 0.64 | DPP4 (0.37) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL13563255 | 0.51 | DPP4 (0.39) | DPP4DPP7DPP8 | |
| SCHEMBL13624977 | 0.50 | GAA (0.30) | — | |
| SCHEMBL22590473 | 0.49 | DPP4 (0.38) | DPP4DPP7DPP8 | |
| SCHEMBL11324356 | 0.49 | — | — | |
| SCHEMBL12903289 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070173-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-06-21 | — | — | WO | disclosed |