Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 18/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524498 | 0.88 | TNFRSF1A (0.61) | TNFRSF1AABCG2 | |
| SCHEMBL14524500 | 0.86 | TNFRSF1A (0.64) | TNFRSF1AABCG2 | |
| SCHEMBL14524493 | 0.85 | TNFRSF1A (0.58) | TNFRSF1AABCG2 | |
| SCHEMBL14524479 | 0.85 | TNFRSF1A (0.56) | TNFRSF1AABCG2 | |
| SCHEMBL4727718 | 0.84 | TNFRSF1A (0.68) | TNFRSF1AABCG2 | |
| SCHEMBL4727721 | 0.84 | TNFRSF1A (0.68) | TNFRSF1AABCG2 | |
| SCHEMBL5560854 | 0.84 | TNFRSF1A (0.57) | TNFRSF1AABCG2 | |
| SCHEMBL5560859 | 0.84 | TNFRSF1A (0.57) | TNFRSF1AABCG2 | |
| SCHEMBL14524496 | 0.83 | TNFRSF1A (0.54) | TNFRSF1AABCG2 | |
| SCHEMBL14524482 | 0.82 | TNFRSF1A (0.54) | TNFRSF1AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093453-A1 | Sulfonamide-substituted chalcone derivatives and their use to treat diseases | ATHEROGENICS, INC. (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093453-A1 | Sulfonamide-substituted chalcone derivatives and their use to treat diseases | STS, HPSE, SULT1E1 | TNFRSF1A 3941/4885ABCG2 7/4885HDAC1 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.