Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.69 |
| ▸ | HTR2A | P28223 | 16/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527161 | 0.90 | HTR2C (0.57) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1436098 | 0.77 | HTR2C (0.64) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25420142 | 0.77 | HTR2C (0.66) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25420145 | 0.77 | HTR2C (0.66) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30488389 | 0.77 | HTR2C (0.66) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31494780 | 0.75 | HTR2C (0.62) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25630091 | 0.75 | HTR2C (0.62) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9202067 | 0.74 | HDAC6 (0.45) | — | |
| SCHEMBL31494797 | 0.74 | HTR2C (0.62) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25630090 | 0.74 | HTR2C (0.62) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208505-B2 | β3 adrenergic agonists | ELI LILLY AND COMPANY (US) | 2007-04-24 | — | — | US | disclosed |