Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12267469 | 0.91 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL14527588 | 0.88 | — | — | |
| SCHEMBL10224774 | 0.88 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2PTGER1PTGER4PTGER3 | |
| SCHEMBL12856340 | 0.87 | CYSLTR2 (0.45) | CYSLTR1CYSLTR2 | |
| SCHEMBL14620846 | 0.85 | CYSLTR2 (0.44) | CYSLTR1CYSLTR2 | |
| SCHEMBL1397232 | 0.85 | CYSLTR2 (0.45) | CYSLTR1CYSLTR2 | |
| SCHEMBL1397268 | 0.85 | CYSLTR2 (0.45) | CYSLTR1CYSLTR2 | |
| SCHEMBL13699137 | 0.81 | CYP2C8 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL2028786 | 0.81 | CYP2C8 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL626376 | 0.81 | CYP2C8 (0.56) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057227-A1 | PROCESS FOR MAKING MONTELUKAST AND INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057225-A2 | PROCESS FOR MAKING MONTELUKAST AND INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057228-A1 | A NEW INTERMEDIATE FOR MAKING MONTELUKAST AND RELATED COMPOUNDS | SYNTHON B.V. (NL) | 2007-05-24 | — | — | WO | disclosed |