Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607854 | 0.78 | IDO1 (0.53) | IDO1TDO2AOC3 | |
| SCHEMBL2336595 | 0.78 | IDO1 (0.51) | IDO1TDO2AOC3HDAC4HDAC7 | |
| SCHEMBL14607856 | 0.74 | IDO1 (0.45) | IDO1TDO2AOC3 | |
| SCHEMBL14528133 | 0.74 | IDO1 (0.61) | IDO1TDO2 | |
| SCHEMBL14607959 | 0.74 | IDO1 (0.57) | IDO1TDO2 | |
| SCHEMBL25264955 | 0.72 | IDO1 (0.39) | IDO1TDO2AOC3HDAC4HDAC7 | |
| SCHEMBL30414866 | 0.72 | IDO1 (0.39) | IDO1TDO2AOC3HDAC4HDAC7 | |
| SCHEMBL25189449 | 0.72 | IDO1 (0.39) | IDO1TDO2AOC3HDAC4HDAC7 | |
| SCHEMBL28595236 | 0.70 | HDAC4 (0.40) | IDO1TDO2AOC3HDAC4HDAC7 | |
| SCHEMBL5540257 | 0.70 | IDO1 (0.51) | IDO1TDO2AOC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790337-A2 | Methods and compounds for treating depression and other disorders | NPS PHARMACEUTICALS, INC. (US) | 2007-05-30 | — | — | EP | disclosed |