Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 19/20 | 0.60 |
| ▸ | CHUK | O15111 | 6/20 | 0.60 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688652 | 0.84 | IKBKB (0.80) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL4588693 | 0.84 | IKBKB (0.66) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL4689143 | 0.79 | IKBKB (0.75) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL14018294 | 0.77 | IKBKB (0.69) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL552955 | 0.76 | IKBKB (0.67) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL4590178 | 0.76 | IKBKB (0.66) | IKBKBCHUKBTKAURKAFLT3 | |
| Hydrochloric Acid SCHEMBL552987 | 0.75 | IKBKB (0.66) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL4589503 | 0.75 | IKBKB (0.65) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL3796938 | 0.75 | IKBKB (1.00) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL4688449 | 0.74 | IKBKB (0.98) | IKBKBCHUKBTKCSF1RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062318-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |