Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 19/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | HTR1D | P28221 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | HTR5A | P47898 | 1/20 | 1.00 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702219 | 1.00 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL5127692 | 1.00 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL175710 | 1.00 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL14528345 | 0.92 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL14276543 | 0.92 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL5124599 | 0.92 | NPY5R (1.00) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL5382521 | 0.88 | NPY5R (0.81) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL14408821 | 0.88 | NPY5R (0.81) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL14276589 | 0.88 | NPY5R (0.83) | NPY5RADRB2CYP3A4HTR1AHTR1D | |
| SCHEMBL5130637 | 0.88 | NPY5R (0.83) | NPY5RADRB2CYP3A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183245-B1 | SELECTIVE NPY (Y5) ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2007-05-09 | — | — | EP | disclosed |