Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 16/20 | 0.55 |
| ▸ | SLC5A1 | P13866 | 15/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528652 | 0.89 | SLC5A1 (0.48) | SLC5A2SLC5A1SLC6A4HRH1 | |
| SCHEMBL12152978 | 0.84 | SLC5A2 (0.77) | SLC5A2SLC5A1SLC6A4 | |
| SCHEMBL14528273 | 0.83 | SLC5A2 (0.57) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528270 | 0.82 | SLC5A2 (0.71) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528391 | 0.81 | SLC5A1 (0.56) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528213 | 0.81 | SLC5A2 (0.72) | SLC5A2SLC5A1SLC6A4HRH1 | |
| SCHEMBL14528271 | 0.80 | SLC5A2 (0.54) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528389 | 0.80 | SLC5A2 (0.56) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528390 | 0.79 | SLC5A2 (0.53) | SLC5A2SLC5A1HRH1 | |
| SCHEMBL14528378 | 0.78 | SLC5A1 (0.54) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783110-A1 | NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-09 | — | — | EP | disclosed |