Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.47 |
| ▸ | FES | P07332 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | FRK | P42685 | 1/20 | 0.43 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.43 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13759345 | 0.88 | TYK2 (0.38) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL429098 | 0.78 | TYK2 (0.53) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL428249 | 0.77 | TYK2 (0.50) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL429031 | 0.77 | TYK2 (0.53) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL3110594 | 0.77 | TYK2 (0.53) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL14530471 | 0.72 | TYK2 (0.64) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL1617732 | 0.72 | TYK2 (0.61) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL1880231 | 0.69 | TYK2 (0.66) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL3100746 | 0.68 | TYK2 (0.67) | TYK2SYKIRAK4BRSK1FES | |
| SCHEMBL3117453 | 0.67 | PIK3CA (0.52) | TYK2SYKIRAK4BRSK1FES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050980-A2 | PROCESS FOR PREPARING MESYLATE SALTS OF IL-12 INHIBITORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2007-05-03 | — | — | WO | disclosed |