SCHEMBL145312

SCHEMBL145312

NC1CC[N]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668050 1.00
SCHEMBL665223 1.00
SCHEMBL195917 0.81
SCHEMBL195918 0.81
SCHEMBL1579034 0.81
SCHEMBL554844 0.79
SCHEMBL146206 0.79
SCHEMBL5868642 0.71
SCHEMBL554942 0.69
SCHEMBL1858589 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201916-A Piperazinylsulfonylaryl compounds for the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-06-14 CN claimed
US-20240150326-A1 CARBOXAMIDE COMPOUNDS AND USES THEREOF INCYTE CORPORATION 2024-05-09 US claimed
US-20240150362-A1 Substituted Pyrrolotriazines MOLECURE S.A. (PL) 2024-05-09 US claimed
CN-112292380-B N- (phenyl) -2- (phenyl) pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for the treatment of cancer 因赛特公司 2024-04-05 CN claimed
WO-2024042494-A1 SUBSTITUTED PYRROLOTRIAZINES MOLECURE SA (PL) 2024-02-29 WO claimed
US-11866426-B2 Benzothiazole compounds and uses thereof INCYTE CORPORATION (US) 2024-01-09 US claimed
CN-112204028-B tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2023-12-29 CN claimed
EP-3334710-B1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-10-04 EP claimed
EP-3802539-B1 TETRAHYDRO-1H-PYRAZINO[2,1-A]ISOINDOLYLQUINOLINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE HOFFMANN LA ROCHE (CH) 2023-09-20 EP claimed
US-20230219973-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF MOLECURE S.A. (PL) 2023-07-13 US claimed
US-4616019-A ANTIBIOTIC ABBOTT LABORATORIES (US) 1986-10-07 US claimed
US-4607032-A Quino-benoxazine antibacterial compounds ABBOTT LABORATORIES (US) 1986-08-19 US claimed
EP-0162333-A1 Quino-benzothiazine antibacterial compounds ABBOTT LABORATORIES (US) 1985-11-27 EP claimed
EP-0160284-A1 Quino-benoxazine antibacterial compounds ABBOTT LABORATORIES (US) 1985-11-06 EP claimed
EP-0154780-A1 Quinoline antibacterial compounds ABBOTT LABORATORIES (US) 1985-09-18 EP claimed
EP-0153580-A1 Naphthyridine antibacterial compounds ABBOTT LABORATORIES (US) 1985-09-04 EP claimed
US-4539401-A Pyridobenzoxazine derivatives useful as antibacterial agents DAIICHI SEIYAKU CO., LTD. (JP) 1985-09-03 US claimed
US-4535161-A ANTIBIOTIC, BACTERICIDE DAIICHI SEIYAKU CO., LTD. (JP) 1985-08-13 US claimed
US-4533663-A Quino-benzothiazine antibacterial compounds ABBOTT LABORATORIES (US) 1985-08-06 US claimed
EP-0101829-A2 Tricyclic compounds, a process for their production and pharmaceutical compositions containing said compounds DAIICHI SEIYAKU CO., LTD. (JP) 1984-03-07 EP claimed