Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833828 | 0.91 | HDAC6 (0.41) | KLKB1MAPTTHRBHDAC6HDAC3 | |
| SCHEMBL12833503 | 0.81 | TSHR (0.44) | KLKB1MAPTTHRBHDAC6HDAC3 | |
| SCHEMBL14090733 | 0.80 | HDAC6 (0.41) | KLKB1MAPTTHRBHDAC6HDAC3 | |
| SCHEMBL12833914 | 0.80 | MAPT (0.42) | KLKB1MAPTTHRBHDAC6HDAC3 | |
| SCHEMBL12833490 | 0.79 | HDAC6 (0.42) | KLKB1MAPTHDAC6HDAC3HDAC1 | |
| SCHEMBL14531473 | 0.79 | TLR8 (0.42) | KLKB1MAPTHDAC6HDAC3HDAC1 | |
| SCHEMBL12834183 | 0.79 | HDAC3 (0.40) | KLKB1MAPTTHRBHDAC6HDAC3 | |
| SCHEMBL12833753 | 0.78 | HDAC6 (0.41) | KLKB1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1761968 | 0.78 | COMT (0.46) | MAPTTHRBHDAC6HDAC3HDAC1 | |
| SCHEMBL12833930 | 0.78 | SLC5A7 (0.42) | KLKB1HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056155-A1 | HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE MODULATORS | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |