Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386171 | 1.00 | EPHX2 (0.32) | EPHX2CNR1CNR2 | |
| SCHEMBL1604681 | 0.85 | TSHR (0.35) | EPHX2CNR1 | |
| SCHEMBL1605621 | 0.74 | — | — | |
| SCHEMBL1605484 | 0.74 | — | — | |
| SCHEMBL6506039 | 0.74 | MAPT (0.36) | EPHX2CNR1CNR2 | |
| SCHEMBL1605333 | 0.72 | — | — | |
| SCHEMBL1607146 | 0.71 | KMT2A (0.39) | EPHX2CNR1CNR2 | |
| SCHEMBL1690381 | 0.71 | — | — | |
| SCHEMBL1605753 | 0.70 | CNR1 (0.30) | CNR1CNR2 | |
| SCHEMBL1605267 | 0.70 | CYP1A2 (0.42) | EPHX2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061661-A2 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | AMGEN INC. (US) | 2007-05-31 | — | — | WO | disclosed |