⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645298 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8460072 | 0.65 | — | — | |
| SCHEMBL630634 | 0.65 | HDAC6 (0.41) | — | |
| SCHEMBL2101505 | 0.63 | AURKA (0.56) | — | |
| SCHEMBL30659527 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL7988951 | 0.62 | HDAC6 (0.40) | — | |
| SCHEMBL1422273 | 0.61 | — | — | |
| SCHEMBL445228 | 0.61 | — | — | |
| SCHEMBL2850012 | 0.61 | DAO (0.37) | — | |
| SCHEMBL31512727 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204028-B | tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | claimed |
| EP-4249479-A1 | GLUCOSIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Beijing Increase Innovative Drug Co., Ltd. (CN) | 2023-09-27 | — | — | EP | claimed |
| CN-113817703-B | Transaminase mutants and uses thereof | 凯莱英生命科学技术(天津)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-113736759-B | Transaminase mutants and uses thereof | 凯莱英生命科学技术(天津)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-113817702-B | Transaminase mutants and uses thereof | 凯莱英生命科学技术(天津)有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-114763312-A | Method for inducing H halogenation in C-H on benzene ring or heterocyclic ring by ultraviolet light | 中国科学院大连化学物理研究所 | 2022-07-19 | — | — | CN | claimed |
| US-20220220519-A1 | Transaminase mutant and use thereof | ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) | 2022-07-14 | — | — | US | claimed |
| CN-114539231-A | Glucoside derivative and preparation method and application thereof | 北京盈科瑞创新药物研究有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-3964571-A1 | TRANSAMINASE MUTANT AND APPLICATION THEREOF | Asymchem Life Science (Tianjin) Co., Ltd. (CN) | 2022-03-09 | — | — | EP | claimed |
| CN-113817703-A | Transaminase mutants and uses thereof | 凯莱英生命科学技术(天津)有限公司 | 2021-12-21 | — | — | CN | claimed |
| WO-2002062807-A1 | PHTHALIC ACID DIAMIDE, METHOD FOR THE PRODUCTION THEREOF AND THE USE OF THE SAME AS A PESTICIDE | BAYER CROPSCIENCE AG (DE) | 2002-08-15 | — | — | WO | claimed |
| US-6420393-B1 | NUCLEAR FACTOR .KAPPA.B-DEPENDENT DISEASE SELECTED FROM THE GROUP CONSISTING OF INFLAMMATORY DISEASES, IMMUNOLOGICAL DISORDERS, SEPTIC SHOCK, TRANSPLANT REJECTION, RADIATION DAMAGE, REPERFUSION INJURIES AFTER ISCHEMIA, STROKE OR | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | claimed |
| EP-1102761-A2 | CYCLOPENTABENZOFURAN DERIVATIVES AND THEIR USE | Bayer Aktiengesellschaft (DE) | 2001-05-30 | — | — | EP | claimed |
| WO-2000008007-A2 | CYCLOPENTABENZOFURAN DERIVATIVES AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-17 | — | — | WO | claimed |
| EP-0860435-A1 | Pyridazin-3-one derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-08-26 | — | — | EP | claimed |
| EP-0749419-A1 | OXIME DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1996-12-27 | — | — | EP | claimed |
| EP-0439785-B1 | Substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic acid ester | BAYER AG (DE) | 1995-09-27 | — | — | EP | claimed |
| WO-1995024383-A1 | OXIME DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-14 | — | — | WO | claimed |
| US-5262416-A | Insecticides or fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-16 | — | — | US | claimed |
| EP-0439785-A2 | Substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic acid ester | BAYER AG (DE) | 1991-08-07 | — | — | EP | claimed |