Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NGF | P01138 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14532958 | 0.89 | KDM4E (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL14533060 | 0.87 | KDM4E (0.30) | — | |
| SCHEMBL14533061 | 0.87 | KDM4E (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL14532961 | 0.86 | KDM4E (0.41) | IDH1MEN1KMT2A | |
| SCHEMBL14532895 | 0.86 | HDAC1 (0.41) | IDH1 | |
| SCHEMBL14532891 | 0.84 | KDM4E (0.41) | IDH1MEN1KMT2A | |
| SCHEMBL14532966 | 0.84 | HDAC1 (0.44) | IDH1 | |
| SCHEMBL14532894 | 0.82 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL12870976 | 0.77 | HCRTR1 (0.35) | HCRTR1HCRTR2IDH1MEN1TDP2 | |
| SCHEMBL14532959 | 0.77 | IP6K1 (0.38) | IDH1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223785-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-29 | — | — | US | disclosed |