Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.43 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338493 | 0.86 | PHLPP2 (0.54) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL4338500 | 0.86 | PHLPP2 (0.54) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL13743964 | 0.85 | BRD4 (0.44) | PHLPP2BRD4RPS6KA3PTPN1POLB | |
| SCHEMBL14503644 | 0.82 | PTPN11 (0.46) | PHLPP2BRD4PTPN1POLBPTGS1 | |
| SCHEMBL14469721 | 0.81 | PHLPP2 (0.54) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL9462136 | 0.80 | PHLPP2 (0.56) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL9462138 | 0.80 | PHLPP2 (0.56) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL19235141 | 0.80 | PHLPP2 (0.56) | PHLPP2BRD4RPS6KA3POLBCYP2D6 | |
| SCHEMBL16454194 | 0.79 | PHLPP2 (0.55) | PHLPP2BRD4RPS6KA3PTGS1PTGS2 | |
| SCHEMBL9881394 | 0.78 | PHLPP2 (0.48) | PHLPP2BRD4POLBPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217803-B2 | Benzimidazole-pyridone-based azo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-15 | — | — | US | disclosed |