Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ODC1 | P11926 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31021106 | 0.80 | TOP2A (0.53) | PTPN1DHODHMEN1LMNAMAPT | |
| SCHEMBL31021107 | 0.80 | TOP2A (0.53) | PTPN1DHODHMEN1LMNAMAPT | |
| SCHEMBL4479470 | 0.80 | PTPN1 (0.48) | PTPN1DHODHMEN1LMNAMAPT | |
| SCHEMBL4479473 | 0.80 | PTPN1 (0.48) | PTPN1DHODHMEN1LMNAMAPT | |
| SCHEMBL29435848 | 0.67 | BACE1 (0.47) | PTPN1DHODHMEN1LMNAMAPT | |
| Lespeol SCHEMBL5522457 | 0.67 | PTPN1 (0.69) | PTPN1DHODHMEN1LMNAMAPT | |
| Isobavachalcone SCHEMBL600137 | 0.65 | PTPN1 (1.00) | PTPN1DHODHMEN1LMNAMAPT | |
| Xanthoangelol SCHEMBL5519356 | 0.64 | MEN1 (1.00) | PTPN1DHODHMEN1LMNAMAPT | |
| Xanthoangelol SCHEMBL5519362 | 0.64 | MEN1 (1.00) | PTPN1DHODHMEN1LMNAMAPT | |
| Xanthoangelol SCHEMBL454823 | 0.64 | MEN1 (1.00) | PTPN1DHODHMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112066-A1 | Remedy | TAKARA BIO INC. (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112066-A1 | Remedy | AKR1B1, AKR1C2, ALDOA | PTPN1 1047/4885DHODH 353/4885MEN1 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.