Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 19/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757360 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL757361 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL759687 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL758409 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL759686 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL760204 | 0.89 | CETP (0.69) | CETPKCNH2 | |
| SCHEMBL13092072 | 0.81 | CETP (0.52) | CETPKCNH2KIF11 | |
| SCHEMBL760050 | 0.80 | CETP (0.74) | CETPKCNH2KIF11 | |
| SCHEMBL758720 | 0.76 | CETP (0.62) | CETPKCNH2 | |
| SCHEMBL758655 | 0.76 | CETP (0.62) | CETPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |