SCHEMBL14534705

SCHEMBL14534705

O=C(NC1CCCC1)N[C@](Cc1ccccc1)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(O)cn1

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1183274 0.93 CETP (1.00) CETP
SCHEMBL1181936 0.93 CETP (0.90) CETP
SCHEMBL1183277 0.93 CETP (1.00) CETP
SCHEMBL1181937 0.93 CETP (0.90) CETP
SCHEMBL1182412 0.93 CETP (0.90) CETP
SCHEMBL1184099 0.93 CETP (1.00) CETP
SCHEMBL1183461 0.91 CETP (0.87) CETP
SCHEMBL1184161 0.91 CETP (0.96) CETP
SCHEMBL1184159 0.91 CETP (0.96) CETP
SCHEMBL1181683 0.91 CETP (1.00) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007062314-A2 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-31 WO disclosed