Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.77 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.69 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421644 | 0.91 | DPP4 (0.74) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8377886 | 0.88 | DPP4 (0.94) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8377973 | 0.88 | DPP4 (0.94) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL7858456 | 0.88 | DPP4 (0.94) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL7852579 | 0.88 | DPP4 (0.94) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8289074 | 0.87 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4664756 | 0.87 | DPP4 (0.68) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4958143 | 0.85 | DPP4 (0.76) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL7852588 | 0.85 | DPP4 (0.73) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8290050 | 0.85 | DPP4 (0.69) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053819-A2 | PYRROLIDINYL BETA-AMINO AMIDE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |