Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 17/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4160874 | 0.88 | CASR (0.69) | CASRNR1I2 | |
| SCHEMBL4148326 | 0.86 | CASR (0.68) | CASRNR1I2 | |
| SCHEMBL4143299 | 0.86 | CASR (0.74) | CASRNR1I2KDM4EMEN1MAPT | |
| SCHEMBL4143317 | 0.85 | CASR (0.81) | CASRNR1I2 | |
| SCHEMBL4143340 | 0.85 | CASR (0.76) | CASRNR1I2 | |
| SCHEMBL4135287 | 0.85 | CASR (0.69) | CASRNR1I2TSHRHSD17B10 | |
| SCHEMBL4147429 | 0.84 | CASR (1.00) | CASRNR1I2 | |
| SCHEMBL4157964 | 0.84 | CASR (0.75) | CASRNR1I2 | |
| SCHEMBL4151003 | 0.84 | CASR (0.80) | CASRNR1I2 | |
| SCHEMBL4138478 | 0.83 | CASR (0.73) | CASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |