SCHEMBL145360

SCHEMBL145360

OC(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14817620 0.78
SCHEMBL4443792 0.78
SCHEMBL1748127 0.78
SCHEMBL10945109 0.78
SCHEMBL6439536 0.78
SCHEMBL14721530 0.72
SCHEMBL5146 0.72
SCHEMBL3881 0.72
SCHEMBL23396 0.72
SCHEMBL9376 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3055 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3183237-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE Bayer CropScience Aktiengesellschaft (DE) 2017-06-28 EP claimed
EP-3083565-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES Bayer CropScience Aktiengesellschaft (DE) 2016-10-26 EP claimed
EP-3083566-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES Bayer CropScience Aktiengesellschaft (DE) 2016-10-26 EP claimed
WO-2016026789-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES STARTING FROM HEXAFLUOROPROPENE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO claimed
WO-2015078846-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES BAYER CROPSCIENCE AG (DE) 2015-06-04 WO claimed
WO-2015078847-A1 PROCESS FOR THE PREPARATION OF 5-FLUORO-1H-PYRAZOLES BAYER CROPSCIENCE AG (DE) 2015-06-04 WO claimed
EP-0708107-B1 Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHINETSU CHEMICAL CO (JP) 2001-02-28 EP claimed
EP-0708106-B1 Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHINETSU CHEMICAL CO (JP) 2000-08-09 EP claimed
EP-0505560-B1 STABILIZATION OF CHLOROFLUOROCARBON COMPOSITIONS BAXTER INT (US) 1997-03-12 EP claimed
EP-0505560-A1 STABILIZATION OF CHLOROFLUOROCARBON COMPOSITIONS. BAXTER INT (US) 1992-09-30 EP claimed
US-5114608-A Refluxing hollow fibers in a chlorofluorocarbon-alcohol blend and generation of hydrogen chloride, mixing with a scavenger BAXTER INTERNATIONAL INC. (US) 1992-05-19 US claimed
WO-1992007059-A1 STABILIZATION OF CHLOROFLUOROCARBON COMPOSITIONS BAXTER INTERNATIONAL INC. (US) 1992-04-30 WO claimed
US-4962118-A ACTIVE AGAINST ASPERGILLUS, CHAETOMIUM, PENICILLUM; WHEAT, BARLEY BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US claimed
EP-0232538-B1 5-ACYLAMIDO-1-ARYL PYRAZOLES BAYER AG (DE) 1990-05-23 EP claimed
EP-0222253-B1 SUBSTITUTED 5-AMINO-1-ARYL-PYRAZOLES BAYER AG (DE) 1989-04-05 EP claimed
US-4802910-A Herbicidal acylated sulphonylguanidines BAYER AKTIENGESELLSCHAFT (DE) 1989-02-07 US claimed
CN-115232117-B Substituted isoxazole pyrimidine amine compound, preparation method and application thereof 沈阳中化农药化工研发有限公司 2024-07-16 CN disclosed
CN-115052875-B 4- (4, 5-Dihydroisoxazol-3-yl) thiazol-2-yl) piperidine-thioimine or sulphoxide-imine derivatives and related compounds as fungicides for crop protection PI工业有限公司 2024-07-12 CN disclosed
US-3995062-A INHALATION ANESTHETICS W. R. GRACE & CO. (US) 1976-11-30 US disclosed
US-3932529-A GENERAL INHALATION ANESTHETICS W. R. GRACE & CO. (US) 1976-01-13 US disclosed