Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 4/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.33 |
| ▸ | PDE1A | P54750 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25380100 | 0.89 | PDE1C (0.35) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL13447987 | 0.85 | TNK2 (0.35) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL19264176 | 0.85 | PDE1C (0.33) | PDE1CPDE1APDE1B | |
| SCHEMBL401192 | 0.84 | TNK2 (0.38) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL16748877 | 0.84 | PDE1C (0.44) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL17892665 | 0.83 | PDE1C (0.33) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL17892667 | 0.83 | PDE1C (0.33) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL400651 | 0.83 | PDE1C (0.43) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL18099738 | 0.81 | PDE1C (0.46) | TNK2PDE1CPDE1APDE1B | |
| SCHEMBL13962521 | 0.80 | PDE1C (0.47) | TNK2PDE1CPDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061737-A2 | FUSED BICYCLIC mTOR INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | disclosed |