Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 18/20 | 0.49 |
| ▸ | AURKA | O14965 | 16/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12404635 | 0.84 | AURKB (0.65) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL14537036 | 0.78 | AURKB (0.60) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL8247338 | 0.78 | AURKA (0.73) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL12404508 | 0.76 | AURKA (0.71) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL12404627 | 0.75 | AURKB (0.58) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL12404630 | 0.75 | AURKB (0.67) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL14538650 | 0.75 | AURKA (0.72) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL14538376 | 0.75 | AURKB (0.74) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL12404477 | 0.75 | AURKA (0.66) | AURKBAURKACHEK1LCKKDR | |
| SCHEMBL12404510 | 0.74 | AURKA (0.67) | AURKBAURKACHEK1LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |