Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 5/20 | 0.59 |
| ▸ | IGF1R | P08069 | 15/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19264070 | 0.86 | TNK2 (0.63) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL398156 | 0.84 | TNK2 (0.61) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL10189260 | 0.84 | TNK2 (0.61) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL2967554 | 0.84 | TNK2 (0.61) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL14536933 | 0.77 | TNK2 (0.59) | TNK2IGF1RMAPK3MAPK1 | |
| SCHEMBL19264282 | 0.74 | TNK2 (0.50) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL1129353 | 0.74 | TNK2 (1.00) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL4360606 | 0.74 | TNK2 (1.00) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL23834450 | 0.74 | TNK2 (0.50) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL23834448 | 0.74 | TNK2 (0.50) | TNK2IGF1RCYP3A4MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061737-A2 | FUSED BICYCLIC mTOR INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | disclosed |