Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 15/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246197 | 0.93 | FYN (0.48) | FYNMKNK1MKNK2ADORA2ATTK | |
| SCHEMBL14537012 | 0.76 | FYN (0.40) | FYNTTKAURKA | |
| SCHEMBL14507283 | 0.74 | FYN (0.54) | FYNTTKAURKA | |
| SCHEMBL8240040 | 0.74 | FYN (0.51) | FYNTTKAURKA | |
| SCHEMBL8240300 | 0.72 | FYN (0.54) | FYNTTKAURKA | |
| SCHEMBL8239749 | 0.72 | FYN (0.46) | FYNADORA2ATTKAURKA | |
| SCHEMBL8241033 | 0.72 | FYN (0.55) | FYNTTKAURKA | |
| SCHEMBL13157193 | 0.71 | FYN (0.50) | FYNTTKAURKA | |
| SCHEMBL8239628 | 0.71 | FYN (0.49) | FYNTTKAURKA | |
| SCHEMBL8241040 | 0.70 | FYN (0.52) | FYNTTKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |